Over-use of conventional antimicrobials, pathogen resistance
and a spectrum of emerging organisms leaves the application and
success of current antimicrobial therapies ever more limited. Global
healthcare is facing an unprecedented crisis with a massive current
and predicted future unmet clinical need for effective, safe and
resistance-free therapies to combat bacterial, fungal, viral and
other infectious diseases and conditions.
“Time to go back to the
drawing board”
NovaBiotics Ltd has employed an informed or rational drug design
based approach; looking to nature as the template for engineering
a totally novel class of antimicrobial peptide therapies. Peptide
antimicrobials form the cornerstone of the body’s first
line of defence against the spectrum of potentially harmful micro-organisms
(bacterial, fungus, viruses, protozoa) with which we come into
contact daily.
NovaBiotics has capitalised on the microbicidal properties of
these natural infection-fighting agents and has designed, developed
and applied peptide compounds that lack the problematic properties
that prevent their natural counterparts from being used as therapeutics.
The result is a highly flexible platform technology of potent
antifungal and antibacterial peptides that can be applied for
the treatment and even prevention of a range of fungal and bacterial
infections.
“Taking nature's lead in
antimicrobials”
NovaBiotics' believes its proprietary technology has the potential
to meet the significant and acute need for safer, more effective
antimicrobials, thereby addressing the various and well described
shortcomings of conventional anti-infective therapies. NovaBiotics'
technology is microbicidal rather than merely microbistatic and
its mode of action is such that pathogen resistance is highly
unlikely, if not impossible.
"The emergence of multiple antibiotic-resistant
microorganisms has led to a search for alternatives to traditional
therapeutic regimens.”
Prof A. O. Tzianabos
NovaBiotics
Ltd are proud to be members of the Clinical and Laboratory
Standards Institute. The Clinical and Laboratory Standards
Institute is a global, non-profit organization that promotes
best practices in clinical and laboratory testing throughout
the world, using a consensus-driven process that balances the
viewpoints of industry, government, and the healthcare professions.
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